Thank you to anyone who has already donated - your generous donations helped make three months of treatment possible.
My brother Nate continues to fight stage IV Hodgkin's lymphoma. He's just 31, with a wife and baby girl. They have no active income (since he's been unable to return to work), no insurance, and cannot afford the treatment he needs. Nate and his family need your help. Please consider a donation, every dollar helps. Thanks.
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#!/usr/bin/env ruby @seq = seq end inline do |builder| builder.prefix %{ #define MATCH(A,B) ((equal[A] & equal[B]) != 0) } builder.prefix %{ int equal[256] = { 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1,14, 4,11, 0, 0, 8, 7, 0, 0,10, 0, 5,15, 0, 0, 0, 9,12, 2, 2,13, 3, 0, 6, 0, 0, 0, 0, 0, 0, 0, 1,14, 4,11, 0, 0, 8, 7, 0, 0,10, 0, 5,15, 0, 0, 0, 9,12, 2, 2,13, 3, 0, 6, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 }; } # ss is the start of the string, used only for reporting the match endpoints. builder.c %{ int backtrack(char* ss, char* s, char* p, int mm, int ins, int del) { int r = 0; while (*s && MATCH(*s, *p)) ++s, ++p; // OK to always match longest segment if (!*p) return (s - ss) - 1; else { if (mm && *s && *p && (r = backtrack(ss, s + 1, p + 1, mm - 1, ins, del))) return r; if (ins && *s && (r = backtrack(ss, s + 1, p, mm, ins - 1, del))) return r; if (del && *p && (r = backtrack(ss, s, p + 1, mm, ins, del - 1))) return r; } return 0; } } # Find all occurrences of p starting at any position in s, with at most # mm mismatches, ins insertions and del deletions. builder.c %{ int patscan(char* p, int mm, int ins, int del) { char* s = StringValuePtr(rb_iv_get(self, "@seq")); char* ss; int end; for (ss = s; *s; ++s) { end = backtrack(ss, s, p, mm, ins, del); if (end) return end; } } } end end seq = "tcatcgagtcatcgatcgatcgatcgatcga" pat = "gtcatcga" scanner = Scan.new(seq) puts scanner.patscan(pat, 0, 0, 0) __END__ |